GL1X · GenesisL1 explorer

Ligand · 6ZT

6ZT · (4~{S})-5-[5-chloranyl-2-[2-(dimethylamino) ethoxy]phenyl]-4-(4-chloranyl-2-methyl-phenyl)-2-(2-methoxyphenyl)-3-propan-2-yl-4~{H}-pyrrolo[3,4-c]pyrazol-6-one

6ZT, (4~{S})-5-[5-chloranyl-2-[2-(dimethylamino) ethoxy]phenyl]-4-(4-chloranyl-2-methyl-phenyl)-2-(2-methoxyphenyl)-3-propan-2-yl-4~{H}-pyrrolo[3,4-c]pyrazol-6-one (C32 H34 Cl2 N4 O3, 593.5 g/mol), in the MolNFT structures on GenesisL1…

Component
6ZT
Formula
C32 H34 Cl2 N4 O3
Class
ligand
Structures
1
PDB entries
1

Binding sites

6ZT in 1 structure; the first of them:

  • 5LN2 · Discovery of a novel class of highly potent inhibitors of the P53-MDM2 interaction by… · 6ZT A201 · binds LEU54, LEU57, GLY58, ILE61, MET62, TYR67, GLN72, VAL75 and 5 more

Residues it binds most

ILE 1, LEU 1, TYR 1, VAL 1, GLN 1, GLY 1, HIS 1, MET 1, PHE 1 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • SO4 · Sulfate ion

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