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Ligand · 6ZQ

6ZQ · 3-(2-chlorophenyl)-2-(2-{6-[(diethylamino) methyl]pyridin-2-yl}ethyl)-6-fluoroquinazolin-4(3H)-one

6ZQ, 3-(2-chlorophenyl)-2-(2-{6-[(diethylamino) methyl]pyridin-2-yl}ethyl)-6-fluoroquinazolin-4(3H)-one (C26 H26 Cl F N4 O, 465.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
6ZQ
Formula
C26 H26 Cl F N4 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

6ZQ in 2 structures; the first of them:

  • 5L1E · AMPA subtype ionotropic glutamate receptor GluA2 in complex with noncompetitive inhibitor… · 6ZQ A902 · binds LYS509, LYS511, SER516, PHE517, ASP519, PRO520, TYR616, LEU620 and 5 more
  • 5L1E · AMPA subtype ionotropic glutamate receptor GLUA2 in complex with noncompetitive inhibitor… · 6ZQ A902 · binds LYS509, LYS511, SER516, PHE517, ASP519, PRO520, TYR616, LEU620 and 5 more

Residues it binds most

PHE 8, SER 8, LEU 8, ASN 8, ASP 8, ILE 8, LYS 6, PRO 8, TYR 8, VAL 4 (residue and the binding sites it lines).

Found with

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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