GL1X · GenesisL1 explorer

Ligand · 6ZG

6ZG · ~{N}'-[7-(4-methylphenyl)pyrido[3,4-b]pyrazin-5-yl]butane-1,4-diamine

6ZG, ~{N}'-[7-(4-methylphenyl)pyrido[3,4-b]pyrazin-5-yl]butane-1,4-diamine (C18 H21 N5, 307.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues…

Component
6ZG
Formula
C18 H21 N5
Class
ligand
Structures
2
PDB entries
1

Binding sites

6ZG in 2 structures; the first of them:

  • 5LMA · Human spleen tyrosine kinase kinase domain in complex with azanaphthyridine inhibitor · 6ZG A701 · binds LEU377, GLY378, VAL385, ALA400, VAL433, MET448, GLU449, MET450 and 10 more
  • 5LMA · Human spleen tyrosine kinase kinase domain in complex with azanaphthyridine inhibitor · 6ZG A701 · binds LEU377, GLY378, VAL385, ALA400, GLU449, MET450, ALA451, GLU452 and 7 more

Residues it binds most

LEU 2, ALA 2, GLU 2, GLY 2, MET 2, VAL 2, ARG 2, ASN 2, ASP 2, PRO 2 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide
  • GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.