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Ligand · 6Z9

6Z9 · 3-[(1S)-1,2,3,4-tetrahydronapthalen-1-ylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl) sulfonyl]benzenesulfonamide

6Z9, 3-[(1S)-1,2,3,4-tetrahydronapthalen-1-ylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl) sulfonyl]benzenesulfonamide (C18 H19 F3 N2 O5 S2, 464.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
6Z9
Formula
C18 H19 F3 N2 O5 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

6Z9 in 2 structures; the first of them:

  • 5LLP · Crystal structure of human carbonic anhydrase isozyme XII with… · 6Z9 A302 · binds TRP4, ASN64, SER67, LYS69, THR88, GLN89, HIS91, HIS93 and 13 more
  • 5LLP · Crystal structure of human carbonic anhydrase isozyme XII with 3… · 6Z9 A302 · binds ASN64, LYS69, GLN89, HIS91, HIS93, GLU104, HIS117, VAL119 and 7 more

Residues it binds most

HIS 8, SER 8, THR 8, PRO 8, VAL 8, LEU 8, ALA 8, ASN 8, GLN 8, GLU 8 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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