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Ligand · 6XE

6XE · 6-[[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methyl]quinoline

6XE, 6-[[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methyl]quinoline (C20 H13 F N6, 356.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
6XE
Formula
C20 H13 F N6
Class
ligand
Structures
2
PDB entries
1

Binding sites

6XE in 2 structures; the first of them:

  • 3ZBX · X-ray Structure of c-Met kinase in complex with inhibitor 6-((6-(4… · 6XE A2345 · binds ILE1084, GLY1085, VAL1092, ALA1108, LEU1140, LEU1157, PRO1158, TYR1159 and 10 more
  • 3ZBX · X-ray structure of C-met kinase in complex with inhibitor 6-((6-(4… · 6XE A2345 · binds ILE1084, GLY1085, VAL1092, ALA1108, LEU1140, LEU1157, PRO1158, TYR1159 and 10 more

Residues it binds most

ALA 2, ASN 2, ASP 2, LEU 2, MET 2, TYR 2, ARG 2, GLY 2, ILE 2, PRO 2 (residue and the binding sites it lines).

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