GL1X · GenesisL1 explorer

Ligand · 6WZ

6WZ · 1-[[4-fluoranyl-3-[(3R)-3-methyl-4-[2,2,2-tris(fluoranyl)ethyl]piperazin-1-yl]carbonyl-phenyl]methyl]quinazoline-2,4-dione

6WZ, 1-[[4-fluoranyl-3-[(3R)-3-methyl-4-[2,2,2-tris(fluoranyl)ethyl]piperazin-1-yl]carbonyl-phenyl]methyl]quinazoline-2,4-dione (C23 H22 F4 N4 O3, 478.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
6WZ
Formula
C23 H22 F4 N4 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

6WZ in 2 structures; the first of them:

  • 5KPP · Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione… · 6WZ A1101 · binds ASP766, LEU769, ASP770, TRP861, HIS862, GLY863, ARG878, ILE879 and 10 more
  • 5KPP · Structure of human PARP1 catalytic domain bound to a quinazoline-2, 4(1H,3H)-dione… · 6WZ A1101 · binds ASP766, LEU769, ASP770, TRP861, HIS862, GLY863, ARG878, ILE879 and 10 more

Residues it binds most

TYR 4, ALA 4, ASP 4, GLY 4, ILE 4, ARG 4, GLU 4, HIS 4, LEU 4, PHE 4 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.