GL1X · GenesisL1 explorer

Ligand · 6VN

6VN · 2-[(4-propan-2-ylphenyl)amino]-1-[(1~{S},5~{S})-3,3,5-trimethylcyclohexyl]benzimidazole-5-carboxylic acid

6VN, 2-[(4-propan-2-ylphenyl)amino]-1-[(1~{S},5~{S})-3,3,5-trimethylcyclohexyl]benzimidazole-5-carboxylic acid (C26 H33 N3 O2, 419.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
6VN
Formula
C26 H33 N3 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

6VN in 2 structures; the first of them:

  • 5LGE · Crystal Structure of human IDH1 mutant (R132H) in complex with NADP+ and an Inhibitor… · 6VN B502 · binds LEU120, MET259, VAL276, GLN277, SER280, VAL281, LEU120, TRP124 and 9 more
  • 5LGE · Crystal structure of human IDH1 mutant (R132H) in complex with NADP+ and an inhibitor… · 6VN B502 · binds LEU120, MET259, VAL276, GLN277, SER280, VAL281, LEU120, TRP124 and 9 more

Residues it binds most

VAL 4, ILE 4, MET 4, SER 4, LEU 4, CYS 4, GLN 4, HIS 4, TRP 4, TYR 4 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • ACT · Acetate ion
  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.