GL1X · GenesisL1 explorer

Ligand · 6T9

6T9 · 5-Ethoxy-pyridine-2-carboxylic acid [3-((R)-2-amino-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide

6T9, 5-Ethoxy-pyridine-2-carboxylic acid [3-((R)-2-amino-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide (C19 H19 F3 N4 O3, 408.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB…

Component
6T9
Formula
C19 H19 F3 N4 O3
Class
ligand
Structures
4
PDB entries
2

Binding sites

6T9 in 4 structures; the first of them:

  • 3ZLQ · BACE2 xaperone complex · 6T9 A1398 · binds ASP25, SER26, GLY27, ARG28, GLY29, TYR30, LEU46, ASP48 and 13 more
  • 4J0T · CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Ethoxy-pyridine-2-carboxylic acid… · 6T9 A504 · binds GLY72, GLN73, GLY74, TYR75, LEU91, ASP93, GLY95, SER96 and 13 more
  • 3ZLQ · BACE2 xaperone complex · 6T9 A1398 · binds ASP25, SER26, GLY27, ARG28, GLY29, TYR30, LEU46, ASP48 and 13 more
  • 4J0T · Crystal structure of bace-1 in complex with 5-ethoxy-pyridine-2- carboxylic acid… · 6T9 A504 · binds GLY72, GLN73, GLY74, TYR75, LEU91, ASP93, GLY95, SER96 and 13 more

Residues it binds most

GLY 6, ASP 6, SER 6, THR 6, TYR 6, ILE 6, ALA 6, ARG 6, LEU 6, PHE 6 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • DMS · Dimethyl sulfoxide

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.