Ligand · 6RF
6RF · 4-azanyl-6-[[(1~{S})-1-(6-fluoranyl-3-phenyl-4-piperazin-1-ylcarbonyl-quinolin-2-yl) ethyl]amino]pyrimidine-5-carbonitrile
6RF, 4-azanyl-6-[[(1~{S})-1-(6-fluoranyl-3-phenyl-4-piperazin-1-ylcarbonyl-quinolin-2-yl) ethyl]amino]pyrimidine-5-carbonitrile (C27 H25 F N8 O, 496.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…
- Component
- 6RF
- Formula
- C27 H25 F N8 O
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
6RF in 2 structures; the first of them:
- 5KAE · Crystal structure of human PI3K-gamma in complex with quinoline-containing inhibitor 5g · 6RF A1204 · binds LYS802, VAL803, MET804, PRO810, LEU811, TRP812, ILE831, ILE879 and 9 more
- 5KAE · Crystal structure of human PI3K-gamma in complex with quinoline- containing inhibitor 5G · 6RF A1204 · binds LYS802, VAL803, MET804, PRO810, LEU811, TRP812, ILE831, ILE879 and 9 more
Residues it binds most
ILE 2, LYS 2, MET 2, THR 2, VAL 2, ALA 2, GLU 2, LEU 2, PRO 2, TRP 2 (residue and the binding sites it lines).
Found with
- SO4 · Sulfate ion
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