GL1X · GenesisL1 explorer

Ligand · 6RE

6RE · [[2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3, 4-bis(oxidanyl)oxolan-2-yl]ethylamino]-azanyl-methylidene]azanium

6RE, [[2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3, 4-bis(oxidanyl)oxolan-2-yl]ethylamino]-azanyl-methylidene]azanium (C12 H19 N8 O3 +1, 323.3 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries).…

Component
6RE
Formula
C12 H19 N8 O3 +1
Class
ligand
Structures
3
PDB entries
2

Binding sites

6RE in 3 structures; the first of them:

  • 5K8V · Crystal Structure of Mus musculus Protein Arginine Methyltransferase 4 (CARM1 130-487)… · 6RE A501 · binds PHE138, TYR150, PHE151, TYR154, GLN160, MET163, GLY193, GLY195 and 15 more
  • 5K8V · Crystal structure of mus musculus protein arginine methyltransferase 4 (CARM1 130-487)… · 6RE A501 · binds TYR150, PHE151, TYR154, GLN160, GLY193, GLY195, GLU215, ALA216 and 11 more
  • 6SQ3 · Crystal structure of mouse PRMT6 in complex with inhibitor U1 · 6RE A401 · binds TYR50, TYR54, HIS60, GLY93, GLY95, VAL114, GLU115, ALA116 and 11 more

Residues it binds most

GLU 10, GLY 10, MET 10, SER 10, TYR 10, PHE 8, VAL 10, ALA 10, PRO 9, LYS 8 (residue and the binding sites it lines).

Found with

  • DXE · 1,2-dimethoxyethane
  • EDO · 1,2-ethanediol
  • PEG · Di(hydroxyethyl)ether
  • PG6 · 1-(2-methoxy-ethoxy)-2-{2-[2-(2-methoxy-ethoxy]-ethoxy}-ethane

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.