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Ligand · 6RD

6RD · 5-(1~{H}-indol-3-ylmethyl)-1-methyl-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide

6RD, 5-(1~{H}-indol-3-ylmethyl)-1-methyl-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide (C28 H27 N5 O, 449.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
6RD
Formula
C28 H27 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

6RD in 2 structures; the first of them:

  • 5L87 · Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes… · 6RD A101 · binds ASN13, ALA14, GLU16, PHE17, ASP20, ARG22, VAL23, PHE34 and 3 more
  • 5L87 · Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes… · 6RD A101 · binds ASN13, ALA14, GLU16, PHE17, ASP20, ARG22, VAL23, PHE34 and 3 more

Residues it binds most

LEU 2, PHE 2, ALA 2, ARG 2, ASN 2, ASP 2, GLU 2, LYS 2, VAL 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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