GL1X · GenesisL1 explorer

Ligand · 6PS

6PS · 2,4-dimethyl-5-{3-[(1R)-1-phenylethyl]-1H-pyrazol-5-yl}-1,3-thiazole

6PS, 2,4-dimethyl-5-{3-[(1R)-1-phenylethyl]-1H-pyrazol-5-yl}-1,3-thiazole (C16 H17 N3 S, 283.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues…

Component
6PS
Formula
C16 H17 N3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

6PS in 2 structures; the first of them:

  • 5K0B · Crystal Structure of COMT in complex with 2,4-dimethyl-5-[3-(1-phenylethyl)-1H-pyrazol-5-y… · 6PS A301 · binds MET40, GLY66, ALA67, TYR68, MET89, GLU90, ILE91, GLY117 and 8 more
  • 5K0B · Crystal structure of comt in complex with 2,4-dimethyl-5-[3-(1… · 6PS A301 · binds MET40, GLY66, ALA67, TYR68, MET89, GLU90, ILE91, GLY117 and 8 more

Residues it binds most

ALA 16, GLY 16, MET 16, ARG 16, ASP 16, GLN 16, GLU 16, HIS 16, ILE 16, LYS 16 (residue and the binding sites it lines).

Found with

  • K · Potassium ion
  • CL · Chloride ion
  • PO4 · Phosphate ion
  • CXS · 3-cyclohexyl-1-propylsulfonic acid
  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.