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Ligand · 6NC

6NC · 2,2'-oxybis(N-{[4-(3-{2,6-difluoro-3-[(propane-1-sulfonyl)amino]benzoyl}-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]methyl}acetamide)

6NC, 2,2'-oxybis(N-{[4-(3-{2,6-difluoro-3-[(propane-1-sulfonyl)amino]benzoyl}-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl]methyl}acetamide) (C52 H46 F4 N8 O9 S2, 1067.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
6NC
Formula
C52 H46 F4 N8 O9 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

6NC in 2 structures; the first of them:

  • 5JT2 · BRAFV600E Kinase Domain In Complex with Chemically Linked Vemurafenib Inhibitor… · 6NC A802 · binds GLN461, ILE463, VAL471, ALA481, VAL482, LYS483, LEU505, LEU514 and 37 more
  • 5JT2 · BRAFV600E kinase domain in complex with chemically linked vemurafenib inhibitor… · 6NC A802 · binds GLN461, ILE463, VAL471, ALA481, VAL482, LYS483, LEU505, LEU514 and 37 more

Residues it binds most

LEU 4, PHE 4, GLY 4, ILE 4, SER 4, VAL 4, GLN 4, ALA 4, ASP 4, CYS 4 (residue and the binding sites it lines).

Found with

  • BEN · Benzamidine

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