GL1X · GenesisL1 explorer

Ligand · 6MD

6MD · N-methyladenosine

6MD, N-methyladenosine (C11 H15 N5 O4, 281.3 g/mol), in the MolNFT structures on GenesisL1: bound in 9 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
6MD
Formula
C11 H15 N5 O4
Class
ligand
Structures
9
PDB entries
6

Binding sites

6MD in 9 structures; the first of them:

  • 6ZD5 · Crystal structure of YTHDC1 S378A mutant complex with m6A · 6MD A606 · binds LYS361, SER362, ASN363, ASN364, ASN367, TRP377, ALA378, THR379 and 7 more
  • 6ZD7 · Crystal structure of YTHDC1 T379V mutant complex with m6A · 6MD B606 · binds LYS361, SER362, ASN363, ASN364, ASN367, TRP377, SER378, VAL379 and 7 more
  • 6ZDA · Crystal structure of YTHDC1 M438A mutant complex with m6A · 6MD A601 · binds LYS361, SER362, ASN363, ASN364, ASN367, TRP377, SER378, THR379 and 7 more
  • 7NJC · Crystal structure of the Toxoplasma CPSF4 YTH-domain in complex with a 7 mer m6A-modified… · 6MD B101 · binds LYS452, SER453, ASN454, ARG455, ASN458, TRP468, ALA469, THR470 and 5 more
  • 8VEV · Structure of a mouse IgG antibody antigen-binding fragment (Fab) targeting… · 6MD C301 · binds TRP33, ASN35, GLU50, TRP101, PHE105, TYR34, TRP93, LEU98
  • 8YH3 · A3R-Gi complex bound to m6A · 6MD R801 · binds VAL65, ALA69, MET90, THR94, PHE167, ARG168, MET173, MET176 and 6 more
  • 6ZD5 · Crystal structure of YTHDC1 S378A mutant complex with M6A · 6MD A606 · binds LYS361, SER362, ASN363, ASN367, TRP377, ALA378, LEU380, ARG404 and 4 more
  • 6ZD7 · Crystal structure of YTHDC1 T379V mutant complex with M6A · 6MD B606 · binds LYS361, SER362, ASN363, ASN367, TRP377, SER378, LEU380, ARG404 and 4 more
  • 6ZDA · Crystal structure of YTHDC1 M438A mutant complex with M6A · 6MD A601 · binds LYS361, SER362, ASN363, ASN367, TRP377, SER378, ARG404, TRP428 and 2 more

Residues it binds most

ASN 16, TRP 15, LEU 15, SER 14, ARG 14, MET 12, ASP 13, LYS 13, PRO 9, THR 7 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • TOE · 2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxyl
  • CL · Chloride ion
  • PEG · Di(hydroxyethyl)ether

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.