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Ligand · 6K5

6K5 · [1-{4-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}-3-(chloromethyl)azetidin-3-yl]methanol

6K5, [1-{4-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}-3-(chloromethyl)azetidin-3-yl]methanol (C18 H21 Cl F3 N7 O2, 459.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
6K5
Formula
C18 H21 Cl F3 N7 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

6K5 in 2 structures; the first of them:

  • 5JHB · Structure of Phosphoinositide 3-kinase gamma (PI3K) bound to the potent inhibitor PIKin3 · 6K5 A1201 · binds MET804, SER806, PRO810, TRP812, ILE831, LYS833, ASP836, LEU838 and 12 more
  • 5JHB · Structure of phosphoinositide 3-kinase gamma (PI3K) bound to the potent inhibitor PIKIN3 · 6K5 A1201 · binds MET804, SER806, PRO810, TRP812, ILE831, LYS833, ASP836, LEU838 and 12 more

Residues it binds most

ILE 2, ASP 2, MET 2, ALA 2, GLU 2, LEU 2, LYS 2, PHE 2, PRO 2, SER 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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