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Ligand · 6F2

6F2 · [3-[[4-[6-chloranyl-2-(1,3-dimethylpyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl]pyrazol-1-yl]methyl]phenyl]-(4-methylpiperazin-1-yl)methanone

6F2, [3-[[4-[6-chloranyl-2-(1,3-dimethylpyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl]pyrazol-1-yl]methyl]phenyl]-(4-methylpiperazin-1-yl)methanone (C27 H28 Cl N9 O, 530.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…

Component
6F2
Formula
C27 H28 Cl N9 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

6F2 in 2 structures; the first of them:

  • 5AAG · Aurora A kinase bound to an imidazopyridine inhibitor (14b) · 6F2 A1389 · binds ARG137, LEU139, GLY140, LYS141, VAL147, ALA160, LEU194, LEU210 and 11 more
  • 5AAG · Aurora a kinase bound to an imidazopyridine inhibitor (14B) · 6F2 A1389 · binds ARG137, LEU139, GLY140, LYS141, VAL147, ALA160, LEU194, LEU210 and 11 more

Residues it binds most

LEU 2, ALA 2, ARG 2, GLU 2, GLY 2, TYR 2, GLN 2, LYS 2, PRO 2, THR 2 (residue and the binding sites it lines).

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