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Ligand · 6EL

6EL · 2-[(3~{R})-2,6-bis(oxidanylidene)piperidin-3-yl]isoindole-1,3-dione

6EL, 2-[(3~{R})-2,6-bis(oxidanylidene)piperidin-3-yl]isoindole-1,3-dione (C13 H10 N2 O4, 258.2 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues…

Component
6EL
Formula
C13 H10 N2 O4
Class
ligand
Structures
1
PDB entries
1

Binding sites

6EL in 1 structure; the first of them:

  • 5YJ1 · Mouse Cereblon thalidomide binding domain complexed with R-form thalidomide · 6EL A501 · binds VAL380, HIS381, SER382, TRP383, TRP389, TRP403, PHE405

Residues it binds most

TRP 16, HIS 16, PHE 16, SER 16, VAL 16, THR 4, GLU 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • SO4 · Sulfate ion

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