Ligand · 6E6

6E6 · 1-[(2R)-2,3-dihydroxypropyl]-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile

6E6, 1-[(2R)-2,3-dihydroxypropyl]-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile (C26 H27 F3 N6 O2 S, 544.6 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record…

Component: 6E6
Formula: C26 H27 F3 N6 O2 S
Class: ligand
Structures: 1
PDB entries: 1

Binding sites

6E6 in 1 structure; the first of them:

5DB0 · Menin in complex with MI-352 · 6E6 A612 · binds SER155, LEU177, SER178, GLU179, ASP180, HIS181, ALA182, PHE238 and 13 more

Residues it binds most

GLU 1, TYR 1, ALA 1, MET 1, SER 1, VAL 1, ASP 1, CYS 1, GLY 1, HIS 1 (residue and the binding sites it lines).

Found with

58P · 1-[(2S)-2,3-dihydroxypropyl]-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1 H-indole-2-carbonitrile
SO4 · Sulfate ion
DMS · Dimethyl sulfoxide
PG4 · Tetraethylene glycol

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