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Ligand · 6CB

6CB · 3-amino-N-(2'-amino-6'-methyl[4,4'-bipyridin]-3-yl)-6-(2-fluorophenyl)pyridine-2-carboxamide

6CB, 3-amino-N-(2'-amino-6'-methyl[4,4'-bipyridin]-3-yl)-6-(2-fluorophenyl)pyridine-2-carboxamide (C23 H19 F N6 O, 414.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
6CB
Formula
C23 H19 F N6 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

6CB in 2 structures; the first of them:

  • 5IIS · Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors… · 6CB A402 · binds LEU44, GLY45, PHE49, VAL52, ALA65, LYS67, ILE104, LEU120 and 10 more
  • 5IIS · Design, synthesis and structure activity relationship of potent pan- pim kinase… · 6CB A402 · binds LEU44, GLY45, PHE49, VAL52, ALA65, LYS67, ILE104, LEU120 and 10 more

Residues it binds most

LEU 2, ASP 2, GLU 2, ILE 2, VAL 2, ALA 2, ARG 2, ASN 2, GLY 2, LYS 2 (residue and the binding sites it lines).

Found with

  • PEG · Di(hydroxyethyl)ether

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