Ligand · 685
685 · 2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide
685, 2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide (C20 H23 N5 O2 S, 397.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…
- Component
- 685
- Formula
- C20 H23 N5 O2 S
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
685 in 2 structures; the first of them:
- 3EMG · Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of… · 685 A685 · binds LEU377, GLY378, SER379, PHE382, VAL385, ALA400, LYS402, GLU420 and 11 more
- 3EMG · Discovery and sar of novel 4-thiazolyl-2- phenylaminopyrimidines as potent inhibitors of… · 685 A685 · binds LEU377, GLY378, SER379, PHE382, VAL385, ALA400, LYS402, GLU420 and 11 more
Residues it binds most
GLU 2, LEU 2, ALA 2, GLY 2, MET 2, VAL 2, ASP 2, LYS 2, PHE 2, PRO 2 (residue and the binding sites it lines).
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