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Ligand · 65R

65R · 2-{3-[3-(piperidin-4-yl)propoxy]phenyl}-N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]acetamide

65R, 2-{3-[3-(piperidin-4-yl)propoxy]phenyl}-N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]acetamide (C24 H28 N4 O2 S, 436.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
65R
Formula
C24 H28 N4 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

65R in 2 structures; the first of them:

  • 5HVU · Rho-associated protein kinase 1 (ROCK 1) in complex with a pyridine thiazole piperidine… · 65R A501 · binds ILE82, ARG84, GLY85, PHE87, GLY88, GLU89, VAL90, ALA103 and 15 more
  • 5HVU · Rho-associated protein kinase 1 (rock 1) in complex with a pyridine thiazole piperidine… · 65R A501 · binds ILE82, ARG84, GLY85, PHE87, GLY88, GLU89, VAL90, ALA103 and 15 more

Residues it binds most

GLY 4, GLU 4, PHE 4, ALA 4, ASP 4, LEU 4, MET 4, VAL 4, ARG 4, ILE 4 (residue and the binding sites it lines).

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