Ligand · 65L
65L · [1-[3-fluoranyl-4-[(2-piperidin-4-yloxy-1,6-naphthyridin-7-yl)amino]phenyl]pyrazol-3-yl]methanol
65L, [1-[3-fluoranyl-4-[(2-piperidin-4-yloxy-1,6-naphthyridin-7-yl)amino]phenyl]pyrazol-3-yl]methanol (C23 H23 F N6 O2, 434.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…
- Component
- 65L
- Formula
- C23 H23 F N6 O2
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
65L in 4 structures; the first of them:
- 7VDP · The structure of cyclin-dependent kinase 5 (CDK5) in complex with p25 and Compound 1 · 65L A301 · binds ILE10, GLU12, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81 and 11 more
- 7VDU · The structure of cyclin-dependent kinase 2 (CDK2) in complex with Compound 1 · 65L A301 · binds ILE10, GLY13, THR14, VAL18, ALA31, KCX33, VAL64, PHE80 and 12 more
- 7VDP · The structure of cyclin-dependent kinase 5 (CDK5) in complex with P25 and compound 1 · 65L A301 · binds ILE10, GLU12, VAL18, ALA31, LYS33, VAL64, PHE80, GLU81 and 10 more
- 7VDU · The structure of cyclin-dependent kinase 2 (CDK2) in complex with compound 1 · 65L A301 · binds ILE10, GLY13, VAL18, ALA31, KCX33, PHE80, GLU81, PHE82 and 9 more
Residues it binds most
ASP 6, GLN 6, PHE 6, VAL 6, ALA 6, GLU 6, LEU 6, LYS 6, ASN 6, ILE 6 (residue and the binding sites it lines).
Found with
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