Ligand · 65B
65B · 4-({6-amino-5-bromo-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile
65B, 4-({6-amino-5-bromo-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile (C20 H15 Br N6 O, 435.3 g/mol), in the MolNFT structures on GenesisL1: bound in 8 records (4 PDB entries). Every binding site with its residues…
- Component
- 65B
- Formula
- C20 H15 Br N6 O
- Class
- ligand
- Structures
- 8
- PDB entries
- 4
Binding sites
65B in 8 structures; the first of them:
- 1SV5 · Crystal structure of K103N mutant HIV-1 reverse transcriptase (rt) in complex with… · 65B A600 · binds LEU100, LYS101, LYS102, ASN103, VAL106, VAL179, TYR181, TYR188 and 7 more
- 3M8P · HIV-1 RT with NNRTI TMC-125 · 65B A562 · binds LEU100, LYS101, LYS102, LYS103, VAL106, VAL108, VAL179, ILE180 and 11 more
- 3MEC · HIV-1 Reverse Transcriptase in Complex with TMC125 · 65B A561 · binds PRO95, LEU100, LYS101, LYS102, LYS103, VAL106, VAL108, VAL179 and 12 more
- 3MED · HIV-1 K103N Reverse Transcriptase in Complex with TMC125 · 65B A561 · binds PRO95, LEU100, LYS101, LYS102, ASN103, VAL106, VAL179, ILE180 and 12 more
- 1SV5 · Crystal structure of K103N mutant HIV-1 reverse transcriptase (rt) in complex with… · 65B A600 · binds LEU100, LYS101, LYS102, ASN103, VAL106, VAL179, TYR181, TYR188 and 7 more
- 3M8P · HIV-1 rt with nnrti tmc-125 · 65B A562 · binds LEU100, LYS101, LYS102, LYS103, VAL106, VAL108, VAL179, ILE180 and 11 more
- 3MEC · HIV-1 reverse transcriptase in complex with TMC125 · 65B A561 · binds PRO95, LEU100, LYS101, LYS102, LYS103, VAL106, VAL108, VAL179 and 12 more
- 3MED · HIV-1 K103N reverse transcriptase in complex with TMC125 · 65B A561 · binds PRO95, LEU100, LYS101, LYS102, ASN103, VAL106, VAL179, ILE180 and 12 more
Residues it binds most
VAL 8, TYR 8, LYS 8, LEU 8, PRO 8, HIS 8, PHE 8, TRP 8, GLU 6, GLY 6 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.