Ligand · 633
633 · N-{3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl}propanamide
633, N-{3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl}propanamide (C26 H29 N7 O2, 471.6 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with…
- Component
- 633
- Formula
- C26 H29 N7 O2
- Class
- ligand
- Structures
- 1
- PDB entries
- 1
Binding sites
633 in 1 structure; the first of them:
- 5HG5 · EGFR (L858R, T790M, V948R) in complex with N-{3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]ami… · 633 A9001 · binds LEU718, VAL726, ALA743, CYS775, MET790, GLN791, LEU792, MET793 and 7 more
Residues it binds most
LEU 1, CYS 1, MET 1, ALA 1, ARG 1, ASP 1, GLN 1, GLY 1, PHE 1, PRO 1 (residue and the binding sites it lines).
Found with
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