Ligand · 62R

62R · 4-[2-(4-{[(2R,3S)-2-propyl-1-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}-3-{[5-(trifluoromethyl)thiophen-3-yl]oxy}piperidin-3-yl]carbonyl}piperazin-1-yl)phenoxy]butanoic acid

62R, 4-[2-(4-{[(2R,3S)-2-propyl-1-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}-3-{[5-(trifluoromethyl)thiophen-3-yl]oxy}piperidin-3-yl]carbonyl}piperazin-1-yl)phenoxy]butanoic acid (C35 H38 F6 N4 O6 S, 756.8 g/mol), in the MolNFT structures…

Component: 62R
Formula: C35 H38 F6 N4 O6 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

62R in 2 structures; the first of them:

5HMH · HDM2 in complex with a 3,3-Disubstituted Piperidine · 62R A201 · binds GLN24, LYS51, LEU54, LEU57, GLY58, ILE61, MET62, TYR67 and 13 more
5HMH · HDM2 in complex with a 3,3-disubstituted piperidine · 62R A201 · binds GLN24, LYS51, LEU54, LEU57, GLY58, ILE61, MET62, TYR67 and 13 more

Residues it binds most

LEU 4, TYR 4, LYS 4, GLN 4, HIS 4, ILE 4, PHE 4, VAL 4, GLY 4, MET 4 (residue and the binding sites it lines).

Found with

SO4 · Sulfate ion

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