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Ligand · 61E

61E · 4-(2-chlorophenyl)-8-[3-(dimethylamino)propoxy]-9-hydroxy-6-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione

61E, 4-(2-chlorophenyl)-8-[3-(dimethylamino)propoxy]-9-hydroxy-6-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione (C26 H24 Cl N3 O4, 477.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
61E
Formula
C26 H24 Cl N3 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

61E in 2 structures; the first of them:

  • 3BIZ · Wee1 kinase complex with inhibitor PD331618 · 61E A576 · binds ILE305, GLY306, VAL313, ALA326, ILE327, LYS328, GLU346, VAL360 and 11 more
  • 3BIZ · WEE1 kinase complex with inhibitor PD331618 · 61E A576 · binds ILE305, GLY306, VAL313, ALA326, ILE327, LYS328, GLU346, VAL360 and 11 more

Residues it binds most

GLY 2, ILE 2, ASN 2, ASP 2, GLU 2, VAL 2, ALA 2, CYS 2, LYS 2, PHE 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

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