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Ligand · 5ZQ

5ZQ · 2-[(6S,10S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-[(pyridin-2-yl)methyl]acetamide

5ZQ, 2-[(6S,10S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-[(pyridin-2-yl)methyl]acetamide (C25 H23 Cl N6 O S, 491.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…

Component
5ZQ
Formula
C25 H23 Cl N6 O S
Class
ligand
Structures
2
PDB entries
1

Binding sites

5ZQ in 2 structures; the first of them:

  • 7RN2 · Crystal structure of the first bromodomain of human BRD4 in complex with SJ001010551-2 · 5ZQ A202 · binds TRP81, PRO82, PHE83, GLN85, VAL87, LEU92, LEU94, TYR97 and 6 more
  • 7RN2 · Crystal structure of the first bromodomain of human BRD4 in complex with SJ001010551-2 · 5ZQ A202 · binds TRP81, PRO82, PHE83, GLN85, VAL87, LEU92, LEU94, TYR97 and 6 more

Residues it binds most

LEU 2, TYR 2, ASN 2, ASP 2, CYS 2, GLN 2, ILE 2, MET 2, PHE 2, PRO 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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