Ligand · 5YZ
5YZ · 6-[(5-cyclopropyl-1~{H}-pyrazol-3-yl)amino]-2-[4-[(3-methyl-4-oxidanyl-phenyl)methyl]piperazin-1-yl]-~{N}-prop-2-ynyl-pyrimidine-4-carboxamide
5YZ, 6-[(5-cyclopropyl-1~{H}-pyrazol-3-yl)amino]-2-[4-[(3-methyl-4-oxidanyl-phenyl)methyl]piperazin-1-yl]-~{N}-prop-2-ynyl-pyrimidine-4-carboxamide (C26 H30 N8 O2, 486.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1…
- Component
- 5YZ
- Formula
- C26 H30 N8 O2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
5YZ in 2 structures; the first of them:
- 7FIC · Reversible lysine-targeted probes reveal residence time-based kinase selectivity in vivo · 5YZ A401 · binds LEU139, GLY140, LYS141, GLY142, GLY145, ASN146, VAL147, ALA160 and 16 more
- 7FIC · Reversible lysine-targeted probes reveal residence time-based kinase selectivity in vivo · 5YZ A401 · binds LEU139, GLY140, LYS141, GLY142, GLY145, ASN146, VAL147, ALA160 and 16 more
Residues it binds most
LEU 2, GLY 2, ALA 2, LYS 2, ARG 2, ASN 2, GLU 2, PHE 2, PRO 2, SER 2 (residue and the binding sites it lines).
Found with
- CL · Chloride ion
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