GL1X · GenesisL1 explorer

Ligand · 5Q4

5Q4 · 4-[(2-methoxyphenyl)amino]-~{N}-[4-(4-methylpiperazin-1-yl)phenyl]-2-oxidanylidene-1~{H}-pyridine-3-carboxamide

5Q4, 4-[(2-methoxyphenyl)amino]-~{N}-[4-(4-methylpiperazin-1-yl)phenyl]-2-oxidanylidene-1~{H}-pyridine-3-carboxamide (C24 H27 N5 O3, 433.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding…

Component
5Q4
Formula
C24 H27 N5 O3
Class
ligand
Structures
2
PDB entries
2

Binding sites

5Q4 in 2 structures; the first of them:

  • 5EM7 · EGFR kinase domain mutant TMLR" with pyridone compound 13… · 5Q4 A1102 · binds LEU718, VAL726, ALA743, LYS745, GLU762, MET790, GLN791, LEU792 and 10 more
  • 5EM8 · EGFR kinase domain with pyridone compound 13: 4-[(2-methoxyphenyl)amino]-~{N}-[4-(4-methyl… · 5Q4 A1101 · binds LEU718, ALA743, THR790, GLN791, LEU792, MET793, PRO794, PHE795 and 6 more

Residues it binds most

LEU 2, GLU 2, MET 2, THR 2, ALA 2, ASN 2, ASP 2, GLN 2, GLY 2, PHE 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.