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Ligand · 5NH

5NH · 1,1-dimethylethyl [1-cyclohexyl-2-[3-[[[1-[2-[[2-[[2-(dimethylamino)-2-oxo-1-phenylethyl]amino]-2-oxoethyl]amino]-1,2-dioxoethyl]pentyl]amino]carbonyl]-2-azabicyclo[2.2.1]heptan-2-yl]-2-oxoethyl]carbamate

5NH, 1,1-dimethylethyl [1-cyclohexyl-2-[3-[[[1-[2-[[2-[[2-(dimethylamino)-2-oxo-1-phenylethyl]amino]-2-oxoethyl]amino]-1,2-dioxoethyl]pentyl]amino]carbonyl]-2-azabicyclo[2.2.1]heptan-2-yl]-2-oxoethyl]carbamate (C39 H58 N6 O8, 738.9 g/mol)…

Component
5NH
Formula
C39 H58 N6 O8
Class
ligand
Structures
2
PDB entries
1

Binding sites

5NH in 2 structures; the first of them:

  • 2F9U · HCV NS3 protease domain with NS4a peptide and a ketoamide inhibitor with a P2 norborane · 5NH A999 · binds THR40, GLN41, THR42, PHE43, VAL55, HIS57, ARG109, ARG123 and 13 more
  • 2F9U · HCV NS3 protease domain with NS4A peptide and a ketoamide inhibitor with a P2 norborane · 5NH A999 · binds THR40, GLN41, THR42, PHE43, VAL55, HIS57, ARG109, ARG123 and 13 more

Residues it binds most

ARG 2, ALA 2, PHE 2, SER 2, THR 2, VAL 2, ASP 2, CYS 2, GLN 2, GLY 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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