GL1X · GenesisL1 explorer

Ligand · 5JR

5JR · N-[2-[[3-(3,5-dimethoxyphenyl)-2-oxidanylidene-1-[3-(4-propanoylpiperazin-1-yl)propyl]-4H-pyrimido[4,5-d]pyrimidin-7-yl]amino]phenyl]propanamide

5JR, N-[2-[[3-(3,5-dimethoxyphenyl)-2-oxidanylidene-1-[3-(4-propanoylpiperazin-1-yl)propyl]-4H-pyrimido[4,5-d]pyrimidin-7-yl]amino]phenyl]propanamide (C33 H42 N8 O5, 630.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records…

Component
5JR
Formula
C33 H42 N8 O5
Class
ligand
Structures
2
PDB entries
1

Binding sites

5JR in 2 structures; the first of them:

  • 7V29 · Crystal structure of FGFR4 with a dual-warhead covalent inhhibitor · 5JR B801 · binds LEU473, GLY474, GLU475, GLY476, CYS477, VAL481, ARG483, THR499 and 17 more
  • 7V29 · Crystal structure of FGFR4 with a dual-warhead covalent inhhibitor · 5JR B801 · binds LEU473, GLY474, GLU475, CYS477, VAL481, ARG483, ALA501, LYS503 and 14 more

Residues it binds most

ALA 4, GLU 4, GLY 4, VAL 4, ARG 4, CYS 4, LEU 4, ASP 4, ILE 4, LYS 4 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.