GL1X · GenesisL1 explorer

Ligand · 5HV

5HV · N-[2-(diethylamino)ethyl]-2-{2-[(4-fluorobenzyl)sulfanyl]-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl}-N-{[ 4'-(trifluoromethyl)biphenyl-4-yl]methyl}acetamide

5HV, N-[2-(diethylamino)ethyl]-2-{2-[(4-fluorobenzyl)sulfanyl]-4-oxo-4,5,6,7-tetrahydro-1H-cyclopenta[d]pyrimidin-1-yl}-N-{[ 4'-(trifluoromethyl)biphenyl-4-yl]methyl}acetamide (C36 H38 F4 N4 O2 S, 666.8 g/mol), in the MolNFT structures on…

Component
5HV
Formula
C36 H38 F4 N4 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

5HV in 2 structures; the first of them:

  • 5I9I · Crystal structure of LP_PLA2 in complex with Darapladib · 5HV A501 · binds LEU107, PHE110, LEU111, LEU121, PHE125, GLY152, LEU153, GLY154 and 14 more
  • 5I9I · Crystal structure of LP_PLA2 in complex with darapladib · 5HV A501 · binds LEU107, PHE110, LEU111, LEU121, PHE125, GLY152, LEU153, GLY154 and 14 more

Residues it binds most

LEU 4, PHE 4, ALA 4, GLY 4, HIS 4, GLN 4, SER 4, TRP 4, TYR 4 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.