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Ligand · 5HI

5HI · (3R,5R)-7-[2-(4-fluorophenyl)-4-{[(1S)-2-hydroxy-1-phenylethyl]carbamoyl}-5-(1-methylethyl)-1H-imidazol-1-yl]-3,5-dihydroxyheptanoic acid

5HI, (3R,5R)-7-[2-(4-fluorophenyl)-4-{[(1S)-2-hydroxy-1-phenylethyl]carbamoyl}-5-(1-methylethyl)-1H-imidazol-1-yl]-3,5-dihydroxyheptanoic acid (C28 H34 F N3 O6, 527.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
5HI
Formula
C28 H34 F N3 O6
Class
ligand
Structures
2
PDB entries
1

Binding sites

5HI in 2 structures; the first of them:

  • 3CCZ · Thermodynamic and structure guided design of statin hmg-coa reductase inhibitors · 5HI A876 · binds ARG590, MET657, SER661, VAL683, SER684, ASN686, CYS688, ASP690 and 17 more
  • 3CCZ · Thermodynamic and structure guided design of statin hmg-CoA reductase inhibitors · 5HI A876 · binds ARG590, MET657, SER661, VAL683, SER684, ASN686, CYS688, ASP690 and 17 more

Residues it binds most

SER 8, ALA 8, LEU 8, LYS 8, ARG 8, ASN 8, CYS 8, ASP 8, GLU 8, HIS 8 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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