Ligand · 5H5

5H5 · (2S)-2-({2-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}oxy)propanamide

5H5, (2S)-2-({2-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}oxy)propanamide (C19 H22 N6 O3, 382.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding…

Component: 5H5
Formula: C19 H22 N6 O3
Class: ligand
Structures: 2
PDB entries: 2

Binding sites

5H5 in 2 structures; the first of them:

5DXT · p110alpha with GDC-0326 · 5H5 A1101 · binds ARG770, MET772, SER774, PRO778, TRP780, ILE800, LYS802, ASP810 and 13 more
5DXU · p110delta/p85alpha with GDC-0326 · 5H5 A1101 · binds MET752, SER754, PRO758, TRP760, ILE777, LYS779, ASP787, TYR813 and 11 more

Residues it binds most

ILE 2, ASP 2, MET 2, SER 2, VAL 2, GLU 2, LYS 2, PHE 2, PRO 2, THR 2 (residue and the binding sites it lines).

Found with

EDO · 1,2-ethanediol

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