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Ligand · 5BP

5BP · N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine

5BP, N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine (C13 H12 N6, 252.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
5BP
Formula
C13 H12 N6
Class
ligand
Structures
2
PDB entries
1

Binding sites

5BP in 2 structures; the first of them:

  • 3EJ1 · CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor · 5BP A299 · binds ILE10, VAL18, ALA31, LYS33, GLU51, VAL64, PHE80, GLU81 and 8 more
  • 3EJ1 · CDK2/CYCLINA complexed with a pyrazolopyridazine inhibitor · 5BP A299 · binds ILE10, VAL18, ALA31, LYS33, GLU51, VAL64, PHE80, GLU81 and 8 more

Residues it binds most

ASP 4, GLU 4, LEU 4, PHE 4, VAL 4, GLN 4, ALA 4, HIS 4, ILE 4, LYS 4 (residue and the binding sites it lines).

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