Ligand · 5B3

5B3 · 4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide

5B3, 4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide (C17 H20 N4 O2 S, 344.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component: 5B3
Formula: C17 H20 N4 O2 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

5B3 in 2 structures; the first of them:

3E64 · Fragment based discovery of JAK-2 inhibitors · 5B3 A1 · binds LEU855, GLY856, LYS857, GLY858, ASN859, GLY861, SER862, VAL863 and 13 more
3E64 · Fragment based discovery of JAK-2 inhibitors · 5B3 A1 · binds LEU855, GLY856, LYS857, GLY858, ASN859, GLY861, SER862, VAL863 and 13 more

Residues it binds most

GLY 2, LEU 2, ASN 2, LYS 2, VAL 2, ALA 2, ARG 2, ASP 2, GLU 2, MET 2 (residue and the binding sites it lines).

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