GL1X · GenesisL1 explorer

Ligand · 5A0

5A0 · 6-(2,2-difluoroethyl)-4-[4-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)piperazin-1-yl]thieno[2,3-d]pyrimidine

5A0, 6-(2,2-difluoroethyl)-4-[4-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)piperazin-1-yl]thieno[2,3-d]pyrimidine (C17 H21 F2 N5 S2, 397.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
5A0
Formula
C17 H21 F2 N5 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

5A0 in 2 structures; the first of them:

  • 5DDE · Menin in complex with MI-859 · 5A0 A601 · binds SER155, LEU177, SER178, GLU179, ASP180, HIS181, ALA182, PHE238 and 8 more
  • 5DDE · Menin in complex with mi-859 · 5A0 A601 · binds SER155, LEU177, SER178, GLU179, ASP180, HIS181, ALA182, PHE238 and 8 more

Residues it binds most

TYR 4, GLU 4, MET 4, SER 4, ALA 4, ASN 4, ASP 4, CYS 4, HIS 4, LEU 4 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • DMS · Dimethyl sulfoxide
  • EDO · 1,2-ethanediol
  • PG4 · Tetraethylene glycol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.