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Ligand · 59N

59N · 8-[(trans-4-aminocyclohexyl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7(8H)-one

59N, 8-[(trans-4-aminocyclohexyl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (C27 H30 Cl N7 O, 504.0 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
59N
Formula
C27 H30 Cl N7 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

59N in 2 structures; the first of them:

  • 5DEW · Crystal structure of PAK1 in complex with an inhibitor compound 5 · 59N A601 · binds VAL284, ALA297, ILE298, LYS299, MET301, ILE312, GLU315, ILE316 and 14 more
  • 5DEW · Crystal structure of PAK1 in complex with an inhibitor compound 5 · 59N A601 · binds VAL284, ALA297, ILE298, LYS299, MET301, ILE312, GLU315, ILE316 and 14 more

Residues it binds most

MET 4, VAL 4, ILE 4, LEU 4, GLU 4, ASP 4, ALA 4, ASN 4, GLY 4, LYS 4 (residue and the binding sites it lines).

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