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Ligand · 563

563 · N-[4-({4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}oxy)phenyl]prop-2-enamide

563, N-[4-({4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}oxy)phenyl]prop-2-enamide (C22 H26 N8 O2, 434.5 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site…

Component
563
Formula
C22 H26 N8 O2
Class
ligand
Structures
1
PDB entries
1

Binding sites

563 in 1 structure; the first of them:

  • 5D10 · Kinase domain of cSrc in complex with RL236 · 563 A601 · binds LEU273, GLY274, GLN275, VAL281, ALA293, MET338, GLU339, TYR340 and 5 more

Residues it binds most

GLY 2, LEU 2, MET 2, VAL 2, ALA 2, ASP 2, GLU 2, SER 2, TYR 2, GLN 1 (residue and the binding sites it lines).

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