GL1X · GenesisL1 explorer

Ligand · 527

527 · 5-(3-{[1-(benzylsulfonyl)piperidin-4-yl]amino}phenyl)-4-bromo-3-(carboxymethoxy)thiophene-2-carboxylic acid

527, 5-(3-{[1-(benzylsulfonyl)piperidin-4-yl]amino}phenyl)-4-bromo-3-(carboxymethoxy)thiophene-2-carboxylic acid (C25 H25 Br N2 O7 S2, 609.5 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding…

Component
527
Formula
C25 H25 Br N2 O7 S2
Class
ligand
Structures
3
PDB entries
2

Binding sites

527 in 3 structures; the first of them:

  • 2QBP · Crystal structure of ptp1b-inhibitor complex · 527 A800 · binds ARG24, ALA27, SER28, ASP29, TYR46, ASP48, VAL49, GLU115 and 15 more
  • 9C55 · Crystal structure of human PTPN2 in complex with active site inhibitor · 527 A401 · binds ARG26, SER29, HIS30, ASP31, TYR48, ASP50, VAL51, TYR54 and 15 more
  • 2QBP · Crystal structure of PTP1B-inhibitor complex · 527 A800 · binds ARG24, ALA27, SER28, ASP29, TYR46, ASP48, VAL49, GLU115 and 15 more

Residues it binds most

ASP 3, GLY 3, ARG 3, GLN 3, SER 3, ALA 3, TYR 3, CYS 3, GLU 3, ILE 3 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.