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Ligand · 4ZJ

4ZJ · N-[2-[(3R,4S)-3-fluoranyl-4-methoxy-piperidin-1-yl]pyrimidin-4-yl]-2-methyl-1-propan-2-yl-imidazo[4,5-c]pyridin-6-amine

4ZJ, N-[2-[(3R,4S)-3-fluoranyl-4-methoxy-piperidin-1-yl]pyrimidin-4-yl]-2-methyl-1-propan-2-yl-imidazo[4,5-c]pyridin-6-amine (C20 H26 F N7 O, 399.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
4ZJ
Formula
C20 H26 F N7 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

4ZJ in 2 structures; the first of them:

  • 5CAQ · EGFR kinase domain mutant TMLR" with compound 33" · 4ZJ A1102 · binds LEU718, GLY719, PHE723, VAL726, ALA743, LYS745, GLU762, MET766 and 10 more
  • 5CAQ · EGFR kinase domain mutant "tmlr" with compound 33 · 4ZJ A1102 · binds LEU718, GLY719, PHE723, VAL726, ALA743, LYS745, GLU762, MET766 and 10 more

Residues it binds most

LEU 2, MET 2, GLY 2, ALA 2, ASP 2, CYS 2, GLN 2, GLU 2, LYS 2, PHE 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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