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Ligand · 4ZB

4ZB · (3R)-3-methyl-1-(4-{[2-methyl-1-(propan-2-yl)-1H-imidazo[4,5-c]pyridin-6-yl]amino}pyrimidin-2-yl) pyrrolidine-3-carboxamide

4ZB, (3R)-3-methyl-1-(4-{[2-methyl-1-(propan-2-yl)-1H-imidazo[4,5-c]pyridin-6-yl]amino}pyrimidin-2-yl) pyrrolidine-3-carboxamide (C20 H26 N8 O, 394.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
4ZB
Formula
C20 H26 N8 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

4ZB in 2 structures; the first of them:

  • 5CAN · EGFR kinase domain mutant TMLR" with compound 27" · 4ZB A1102 · binds LEU718, GLY719, PHE723, VAL726, ALA743, LYS745, GLU762, MET766 and 13 more
  • 5CAN · EGFR kinase domain mutant "tmlr" with compound 27 · 4ZB A1102 · binds LEU718, GLY719, PHE723, VAL726, ALA743, LYS745, GLU762, MET766 and 13 more

Residues it binds most

LEU 2, MET 2, CYS 2, GLY 2, ALA 2, ARG 2, ASN 2, ASP 2, GLN 2, GLU 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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