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Ligand · 4Y2

4Y2 · 6-chloro-2-cyclopropyl-N-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-5-methylpyrimidin-4-amine

4Y2, 6-chloro-2-cyclopropyl-N-[(2,4-dimethyl-1,3-thiazol-5-yl)methyl]-5-methylpyrimidin-4-amine (C14 H17 Cl N4 S, 308.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
4Y2
Formula
C14 H17 Cl N4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

4Y2 in 2 structures; the first of them:

  • 5C2A · PDE10 complexed with 6-chloro-2-cyclopropyl-N-[(2,4-dimethylthiazol-5-yl)methyl]-5-methyl… · 4Y2 A803 · binds TYR514, HIS515, LEU625, LEU665, SER667, VAL668, ILE682, TYR683 and 5 more
  • 5C2A · PDE10 complexed with 6-chloro-2-cyclopropyl-N-[(2,4-dimethylthiazol-5… · 4Y2 A803 · binds TYR514, HIS515, LEU625, LEU665, SER667, VAL668, ILE682, TYR683 and 5 more

Residues it binds most

LEU 4, PHE 4, TYR 4, GLN 4, GLU 4, HIS 4, ILE 4, MET 4, SER 4, VAL 4 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion

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