Ligand · 4WE

4WE · 4-({5-fluoro-4-[2-methyl-1-(propan-2-yl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)-N-[2-(piperidin-1-yl) ethyl]benzamide

4WE, 4-({5-fluoro-4-[2-methyl-1-(propan-2-yl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)-N-[2-(piperidin-1-yl) ethyl]benzamide (C25 H32 F N7 O, 465.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component: 4WE
Formula: C25 H32 F N7 O
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

4WE in 2 structures; the first of them:

5BYZ · ERK5 in complex with small molecule · 4WE A401 · binds ILE61, GLY62, TYR66, VAL69, ALA82, LYS84, ILE115, LEU137 and 11 more
5BYZ · ERK5 in complex with small molecule · 4WE A401 · binds ILE61, GLY62, TYR66, VAL69, ALA82, LYS84, ILE115, LEU137 and 11 more

Residues it binds most

ASP 2, ILE 2, LEU 2, SER 2, ALA 2, ASN 2, GLN 2, GLU 2, GLY 2, HIS 2 (residue and the binding sites it lines).

Found with

GOL · Glycerol

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