Ligand · 4TH
4TH · (S)-7-((R)-sec-butoxy)-1-(4-chlorophenyl)-6-methoxy-2-(4-(methyl(pyridin-4-ylmethyl)amino)phenyl)-1,2-dihydroisoquinolin-3(4H)-one
4TH, (S)-7-((R)-sec-butoxy)-1-(4-chlorophenyl)-6-methoxy-2-(4-(methyl(pyridin-4-ylmethyl)amino)phenyl)-1,2-dihydroisoquinolin-3(4H)-one (C33 H34 Cl N3 O3, 556.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…
- Component
- 4TH
- Formula
- C33 H34 Cl N3 O3
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
4TH in 2 structures; the first of them:
- 4ZYI · Discovery of NVP-CGM097 - a highly potent and selective MDM2 inhibitor undergoing phase 1… · 4TH A201 · binds GLN24, LYS51, LEU54, PHE55, LEU57, GLY58, ILE61, MET62 and 10 more
- 4ZYI · Discovery of nvp-CGM097 - a highly potent and selective MDM2 inhibitor undergoing phase 1… · 4TH A201 · binds GLN24, LYS51, LEU54, PHE55, LEU57, GLY58, ILE61, MET62 and 10 more
Residues it binds most
ILE 2, PHE 2, GLN 2, LEU 2, TYR 2, VAL 2, GLY 2, HIS 2, LYS 2, MET 2 (residue and the binding sites it lines).
Found with
- CL · Chloride ion
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