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Ligand · 4RV

4RV · 4-amino-8-(4-methylpyridin-3-yl)cinnoline-3-carboxamide

4RV, 4-amino-8-(4-methylpyridin-3-yl)cinnoline-3-carboxamide (C15 H13 N5 O, 279.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
4RV
Formula
C15 H13 N5 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

4RV in 2 structures; the first of them:

  • 4ZLZ · Crystal Structure of Bruton's Tyrosine Kinase in complex with a substituted Cinnoline · 4RV A705 · binds LEU408, GLY409, THR410, GLY411, VAL416, ALA428, LYS430, THR474 and 10 more
  • 4ZLZ · Crystal structure of BRUTON'S tyrosine kinase in complex with a substituted cinnoline · 4RV A705 · binds LEU408, GLY409, THR410, GLY411, VAL416, ALA428, LYS430, THR474 and 10 more

Residues it binds most

GLY 2, LEU 2, THR 2, ALA 2, ARG 2, ASN 2, ASP 2, CYS 2, GLU 2, LYS 2 (residue and the binding sites it lines).

Found with

  • DMS · Dimethyl sulfoxide
  • IMD · Imidazole
  • IPA · Isopropyl alcohol

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