GL1X · GenesisL1 explorer

Ligand · 4QD

4QD · 8-(3-{[(2S)-1-aminopropan-2-yl]oxy}benzyl)-4-(cyclohexylamino)-1-(3-fluorophenyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one

4QD, 8-(3-{[(2S)-1-aminopropan-2-yl]oxy}benzyl)-4-(cyclohexylamino)-1-(3-fluorophenyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one (C29 H38 F N5 O2, 507.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
4QD
Formula
C29 H38 F N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

4QD in 2 structures; the first of them:

  • 4ZPF · BACE1 in complex with 8-(3-((1-aminopropan-2-yl)oxy)benzyl)-4-(cyclohexylamino)-1-(3-fluor… · 4QD A501 · binds GLY11, GLN12, GLY13, LEU30, ASP32, TYR71, THR72, GLN73 and 17 more
  • 4ZPF · BACE1 in complex with 8-(3-((1-aminopropan-2-YL)OXY)BENZYL)-4… · 4QD A501 · binds GLY11, GLN12, GLY13, LEU30, ASP32, TYR71, THR72, GLN73 and 17 more

Residues it binds most

GLY 2, THR 2, ILE 2, ASP 2, GLN 2, LYS 2, TYR 2, ALA 2, ARG 2, LEU 2 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.