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Ligand · 4P4

4P4 · 8-amino-N-[1-(cyclopropylcarbonyl)azetidin-3-yl]-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

4P4, 8-amino-N-[1-(cyclopropylcarbonyl)azetidin-3-yl]-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide (C22 H20 F N5 O2, 405.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
4P4
Formula
C22 H20 F N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

4P4 in 2 structures; the first of them:

  • 4ZK5 · MAP4K4 in complex with inhibitor GNE-495 · 4P4 A403 · binds VAL31, TYR36, VAL39, LYS41, LEU50, ALA52, LYS54, ALA83 and 10 more
  • 4ZK5 · MAP4K4 in complex with inhibitor gne-495 · 4P4 A403 · binds VAL31, TYR36, VAL39, LYS41, LEU50, ALA52, LYS54, ALA83 and 10 more

Residues it binds most

ALA 2, VAL 2, GLY 2, LEU 2, LYS 2, ASP 2, CYS 2, GLU 2, MET 2, PHE 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • MES · 2-(N-morpholino)-ethanesulfonic acid

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