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Ligand · 4NH

4NH · 4-({4-[(4-aminobut-2-ynyl)oxy]phenyl}sulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide

4NH, 4-({4-[(4-aminobut-2-ynyl)oxy]phenyl}sulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide (C17 H23 N3 O5 S2, 413.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
4NH
Formula
C17 H23 N3 O5 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

4NH in 2 structures; the first of them:

  • 2A8H · Crystal structure of catalytic domain of TACE with Thiomorpholine Sulfonamide Hydroxamate… · 4NH A158 · binds GLY346, THR347, LEU348, GLY349, LEU350, GLU398, LEU401, VAL402 and 10 more
  • 2A8H · Crystal structure of catalytic domain of tace with thiomorpholine sulfonamide hydroxamate… · 4NH A158 · binds GLY346, THR347, LEU348, GLY349, LEU350, GLU398, LEU401, VAL402 and 10 more

Residues it binds most

HIS 4, LEU 4, VAL 4, GLU 4, GLY 4, ALA 4, PRO 4, THR 4, SER 2, TYR 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion

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