Ligand · 4MW

4MW · 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-(4-{[({2-[(3S)-2,6-dioxopiperidin-3-yl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}oxy)acetyl]amino}butyl)acetamide

4MW, 2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-N-(4-{[({2-[(3S)-2,6-dioxopiperidin-3-yl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}oxy)acetyl]amino}butyl)acetamide (C38 H37 Cl N8 O7…

Component: 4MW
Formula: C38 H37 Cl N8 O7 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

4MW in 2 structures; the first of them:

4ZC9 · Crystal Structure of the BRD4a/DB-2-190 complex · 4MW A4000 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, CYS136 and 5 more
4ZC9 · Crystal structure of the BRD4A/DB-2-190 complex · 4MW A4000 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, CYS136 and 5 more

Residues it binds most

LEU 2, TYR 2, ASN 2, ASP 2, CYS 2, ILE 2, MET 2, PHE 2, PRO 2, TRP 2 (residue and the binding sites it lines).

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